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PrepStar

Syringe Filtration with RTC PAL

 


The CHROMTECH PrepStar is a laboratory device for automated sample preparation – based on the PAL RTC or PAL RSI autosampler – and is so far for mainly manually performed laboratory activities such as preparing of dilution series, mixing of different fluids, heating, cleaning, concentrating, reducing, filtering, etc., individually according to customer specifications compiled.

In the following example we present a PrepStar solution for syringe filtration.

In the laboratory syringe filters are very often used to filter small volumes of a solution.
By a technique called pressure filtration, the sample solution in a syringe is manually pressed through the membrane of the syringe filter.
A typical field of application is sample preparation (“clean-up”) in chromatographic analysis methods such as gas and liquid chromatography (GC or HPLC).
The syringe filtration is characterized by only a very small dead volume.
Syringe filters are available in many designs and different pore sizes, with mostly 0.45µm or 0.2µm filters being used.
The manual filtration process described above can be performed automatically using the CHROMTECH SyFi Option for the CTC PAL RTC sampler.
Depending on the application, different filter sizes (diameters) as well as single or multiple use of the filters is possible. Thanks to the automatic tool change, the PAL RTC autosampler enables both the unfiltered solution to be drawn up and the syringe filter to be subsequently picked up from its tray position for filtration of the sample.
The filtration process can either take place in the open sample vial on the sampler tray, or after automatic opening with the help of the PAL Decapper module in a previously sealed sample vial.
Depending on the type and number of syringe filters required for the respective application, different tray configurations are available on request.
 
 
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