GPC - Gel Permeation Chromatography

Gel Permeation Chromatography (GPC) / Size Exclusion Chromatography (SEC) is the technique for rapid and reliable characterization of polymer molecular weight and molecular weight distribution.

The GPC module provides an interactive and automated GPC analysis including recalibration and GPC reporting as well as simplifying the retrieval of GPC data. The GPC module allows flow rate and multi-detector delay corrections and includes Narrow, Broad and Broad on Narrow calibrations.

The GPC module is optional add-on software for the Clarity Chromatography Station (from version 2.3) and Clarity EVAL. The Clarity Chromatography Station is designed to acquire and evaluate data from up to four chromatographs at a time (multi detectors measurement supported). The Clarity Chromatography Station can acquire data from any HPLC system with standard analog output. GPC mode is selectable for any instrument within a station.


Data Acquisition: Simultaneous data acquisition from up to four
four-detector chromatographs (4×4 configuration), detector delay correction for multidetector measurement. Data Processing: The same chromatograms can be evaluated in both standard and GPC modes, multiple peaks and multiple signals are processed in one chromatogram.

GPC Integration

Separate integration tables for GPC and standard evaluation are used. There are extensive possibilities for modifying chromatograms. The chromatogram integration can be changed by entering global parameters or interactively, through the direct graphical modification of the baseline.

GPC Calibrations

Narrow, Broad, Broad on Narrow standard calibration methods combined with Flow Rate correction and Universal calibration. Manual calibration or automated recalibration from sequence. Multiple Broad standards can be used.

GPC Calculations

Polynomial (n= 1-5) curve fits (independent for signals), Mp, Mn, Mw , Mv , Mz, Mz+1 molecular weight averages and polydispersity.


Molecular weight distribution graphs. Overlay: Simultaneously displays a virtually unlimited number of chromatograms. Overlay of dW/d logM vs log M and cumulative height graphs.


Slice Table results, graphs, result and summary tables.

User Calculations

User can define custom calculations in the Result and Summary tables. Using the integrated editor you can create your own columns from the original columns and individual mathematical functions.

GPC Results Table

Displays molecular weight averages together with peak details for active signal. Multiple peaks can be evaluated from one chromatogram.

GPC Summary Result Tables

Displays and prints selected results from all simultaneously displayed chromatograms. Postrun: Automatically displays, prints, exports and starts other programs after the completion of a measurement.


Automatically batch processes, displays, exports or prints any number of chromatograms.


User selectable report sections and WYSIWYG formating of Graphs and Tables.

Imprint · All rights reserved © Chromtech GmbH | Attribution, Credits and Copyrights | generated by MATRIX-CMS

We use cookies to offer you a better browsing experience, personalise content and ads, to provide social media features and to analyse our traffic. Read about how you can control cookie usage by clicking Settings. You consent to our cookies if you continue to use this website.

Please choose which type of cookies you consent to:

(ie. account login related cookies)
(i.e. facebook)
(i.e. youtube)
(ie. Google Analytics)